Objective:To summarize the epidemiology and clinical feathers of rabies in children. Methods:Clinical data of 53 diag-nosed rabies cases in the Children’s Hospital of Chongqing Medical University from November 2006 to December 2011 were retro-spectively analyzed. Results:Age of the 53 children was from 1 year and 3 months to 14 years with an average of 7.5 years. Gender ratio was 2.31∶1. Among the 47 cases which had clearly exposure history,43 were attacked by dogs and 4 scratched by cats;only 7 did rabies vaccination and 1 treated the wound in hospital after the bite,none took immunoglobulin. According to clinical manifesta-tion,77.36% had fever,69.81% had hydrophobia and fear of wind,33.96% had hyperspasmia. Nineteen patients died in hospital,of which 4 did autopsy. Parents of 34 patients gave up the therapy. Conclusions:Rabies is a zoonosis with high mortality and poor prog-nosis;children are of high risk and should be timely realized by parents and doctors.