68例肝移植术后肺部并发症临床分析

Clinical analysis on pulmonary complications following liver transplantation in 68 cases

摘要:

目的：分析肝移植术后肺部并发症的临床特征，指导临床早期干预，提高患者生存率。方法：回顾性分析2006年11月至2011年11月1日收入本院的68例肝移植受者的临床资料，总结分析术后肺部并发症的发生率、发生时间、高危因素或病因、治疗及转归等情况。结果：共60例发生了肺部并发症，发生率为88.2%。胸腔积液59例，占86.8%；肺部感染15例，占22.1%，肺水肿13例，占19.1%；呼吸道出血2例，占2.9%；肺不张1例，占1.5%。结论：胸腔积液、肺部感染、肺水肿是肝移植术后常见的肺部并发症，发生肺部感染患者的预后较差。

Abstract:

Objective：To investigate clinical features of pulmonary complications following liver transplantation in order to guide clini－cal intervention and to increase patients’ survival rate. Methods：Clinical data of 68 liver transplant recipients in our hospital from November 2006 to November 2011 were studied retrospectively. Clinical features of postoperative pulmonary complications including incidences，time of onset，risk factors or causes of morbidity，treatment and outcome were studied and summarized. Results：Sixty（88.2%）patients developed at least one pulmonary complication following liver transplantation. The most frequent complication was pleural ef－fusion（59，86.8%），followed by pneumonia（15，22.1%），pulmonary edema（13，19.1%），respiratory tract bleeding（2，2.9%）and at－electasis（1，1.5%）. Conclusions：Pleural effusion，pneumonia and pulmonary edema are common pulmonary complications following liver transplantation. Patients who develop pneumonia have poor prognosis.