旭化成ACH-10改良技术在低体重儿血液滤过中的临床应用：附8例病例分析

Application of improved Agms ACH-10 technology in clinical hemofiltration for low birth weight children：analysis of eight cases

摘要:

目的：观察ACH-10改良后在低体重儿血液滤过中的应用及对多脏器功能衰竭（multiple organ dysfunction syndrome，MODS）的治疗效果。方法：对8例严重MODS的低体重儿用旭化成ACH-10进行持续静脉血液滤过，观察血压、血钾、尿素氮、肌酐、乳酸等的变化及预后。结果：8例低体重儿均顺利置管，并进行转流，8例均出现采血不良，经泵前稀释后仍顺利进行转流，内环境紊乱及肾功能明显改善；低体温1例，术后低血压1例，经处理后改善，余无血压降低及出血等并发症。结论：旭化成ACH-10经适当改良后能够用于低体重儿血液滤过，有利于改善严重MODS低体重患儿的重要脏器功能，提高抢救成功率。

Abstract:

Objective：To observe the therapeutic effect of improved ACH-10 Asahi Kasei on multiple organ dysfunction syndrome （MODS） in hemofiltration of low birth weight children. Methods：Ongoing continuous venous hemofiltration（CVVHF） by ACH-10 Asahi Kasei was performed on eight low birth weight children with severe MODS. Changes in blood pressure，serum potassium，urea nitrogen，creatinine，lactate，and prognosis were observed. Results：Catheterization and bypass were successfully performed on eight low birth weight children. Blood sampling was not well in all cases，but still successfully bypassed through diluting by the pump. Internal environment disorder and renal function were improved significantly. There was one hypothermia child and one hypotension child after the operation and they were improved after the treatment. No child with lower blood pressure and other complications was observed. Conclusion：Appropriately modified Asahi Kasei ACH-10 can be used in blood hemofiltration for low birth weight children and will help to improve the function of serious important organs of MODS children with low birth weight as well as improve the success rate.