双源CT血管成像在南疆地区汉族与维族健康成人冠状动脉解剖结构的比较分析

Coronary artery anatomy on coronary CT angiography in the healthy Han and Uygur adults in Southern Xinjiang，China：a comparative analysis

摘要:

目的：分析新疆南疆地区汉族及维吾尔族健康体检人群冠状动脉CT血管成像（coronarycomputed tomographic angiog－raphy，CCTA）中冠状动脉分支管径及分布类型、主动脉窦管径的差异和相关性分析。方法：回顾性分析2016年1月至2017年1月喀什地区第一人民医院进行健康体检的维吾尔族及汉族健康人群CCTA资料，随机选取冠状动脉正常人群维吾尔族300例，男性173例，女性127例，年龄40~60岁，平均（50.03±7.82）岁；汉族300例，男193例，女性107例，年龄40~60岁，平均（51.36±8.40）岁；对冠状动脉进行曲面重建（curved planar reformation，CPR）、最大强度投影（maximum intensity projection，MIP）及容积再现（volume rendering，VR）重组，采用美国心脏协会15分段法，测量汉族及维吾尔族人群右冠状动脉、左前降支、回旋支、钝缘支近段、中段的管径、主动脉窦管径及冠脉分布类型的差异性。结果：维吾尔族组与汉族组健康人群中左前降支、回旋支、钝缘支近段、中段管径维吾尔族组大于汉族组，2组差异具有统计学意义（P<0.05）。汉族健康人群组300例中左优势分布类型24例（8.0%），右优势分布类型246例（82.0%），均衡型30例（10.0%）。维吾尔族人群组300例中左优势分布类型104例（34.66%），右优势分布类型184例（61.33%），均衡型12例（4.0%），2组冠状动脉优势分布类型存在统计学差异（P<0.05）。右冠冠状动脉、主动脉窦管径直径2组无统计学差异（P>0.05）。结论：南疆地区维吾尔族、汉族健康成人冠状动脉管径及分布类型的存在差异。

Abstract:

Objective：To investigate the differences in coronary artery branch diameter，distribution type，and aortic sinus diameter on coronary CT angiography（CCTA） between the healthy Han and Uygur adults in Southern Xinjiang，China and their correlation. Methods：A retrospective analysis was performed for the CCTA data of the healthy Han and Uygur adults who underwent physical ex－amination in The First People’s Hospital of Kashgar from January 2016 to January 2017. A total of 300 healthy Uygur adults with normal coronary artery（173 male and 127 female adults aged 40-60 years，with a mean age of 50.03±7.82 years） and 300 healthy Han adults with normal coronary artery（193 male and 107 female adults aged 40-60 years，with a mean age of 51.36±8.40 years） were randomly selected. Curved planar reformation，maximum intensity projection，and volume rendering reconstruction of the coronary artery were performed，and the American Heart Association 15-segment method was used to measure the differences in the diameter of the right coronary artery，the left anterior descending artery，the circumflex coronary artery，and the proximal and middle segments of the obtuse marginal branch，aortic sinus diameter，and the distribution of coronary artery between the Han and Uygur population. Results：Compared with the Han group，the Uygur group had significantly larger diameters of the left anterior descending artery，the circumflex coronary artery，and the proximal and middle segments of the obtuse marginal branch（P<0.05）. Among the 300 healthy Han adults，24（8.0%） were left dominant，246（82.0%） were right dominant，and 30 （10.0%） were balanced. Among the 300 healthy Uygur adults，104（34.66%） were left dominant，184（61.33%） were right dominant，and 12 （4.0%） were balanced；there was a significant difference in the distribution of dominant coronary arteries between the two groups（P<0.05）. There were no significant differences be－tween the two groups in diameter of the right coronary artery and aortic sinus diameter（P>0.05）. Conclusion：There are differences in coronary artery diameter and distribution type between the healthy Uygur and Han adults in Southern Xinjiang.