原发性醛固酮增多症：新型确诊试验进展

Primary aldosteronism： Progress in new confirmatory tests

摘要:

确诊试验在诊断原发性醛固酮增多症的过程中十分重要。目前指南未明确推荐何种确诊试验最为理想，临床常用的经典确诊试验各自仍存在不足，均有待进一步改善。许多研究提出了改良的确诊试验或其他新型确诊试验，诸如坐位盐水负荷试验（seated saline suppression test，SSST）、氯沙坦抑制试验（losarton suppression test，LST）、呋塞米立位试验（furosemide upright test，FUT）、氟氢可的松-地塞米松抑制试验（fludrocortisone-dexamethasone suppression test，FDST）、地塞米松-卡托普利-缬沙坦试验（dexamethasone-captopril-valsartan test，DCVT）等，本文旨在对这些新型确诊试验的研究进展加以阐述。

Abstract:

Confirmatory tests are of vital importance in the diagnosis of primary aldosteronism（PA）. Currently，the guideline does not explicitly recommend which confirmatory test is the most optimal one，and the classical ones commonly used in clinical practice still have their own shortcomings，which need to be further improved. Many studies have proposed modified or other new confirmatory tests，such as seated saline suppression test，losarton suppression test，furosemide upright test，fludrocortisone-dexamethasone suppres－sion test，dexamethasone-captopril-valsartan test. The progress in these new confirmatory tests is reviewed in this paper.