多发性硬化的免疫机制进展及潜在治疗靶点

Progress in the study of multiple sclerosis and potential therapeutic targets

摘要:

多发性硬化（multiple sclerosis，MS）是一种好发于中青年患者的中枢神经系统（central nervous system，CNS）自身免疫性疾病。该病可导致认知、运动、感觉、语言等多种功能障碍。深入探索MS的发病机制，发掘有效的药物作用靶点具有重要意义。本文通过分析、归纳近年来国内外MS的研究进展，旨在为进一步阐明其发病机制及潜在治疗靶点提供借鉴。

Abstract:

Multiple sclerosis is an autoimmune disease of the central nervous system，which is prone to develop in young and middle-aged patients. The disease can lead to a variety of dysfunctions，such as problems with cognition，movement，sensation，and language. It is of great significance to explore the pathogenesis of multiple sclerosis and identify effective drug targets. By analyzing and summa－rizing recent advances in the study of multiple sclerosis at home and abroad，the purpose of this paper is to provide a reference for further elucidating the pathogenesis and potential therapeutic targets of this disease.