早发性卵巢功能不全的颗粒细胞自噬机制研究进展

Advances in studies on the mechanism of autophagy granulosa cells in premature ovarian insufficiency

摘要:

早发性卵巢功能不全（premature ovarian insufficiency，POI）是指年龄不足40岁的女性，出现卵巢功能减退甚至衰竭。POI的发病机制尚不十分明确，目前越来越多的研究发现，颗粒细胞的自噬诱导了POI的发生，本文将对POI的颗粒细胞自噬研究进展进行阐述。

Abstract:

Premature ovarian insufficiency（POI） refers to the decline or even failure of ovarian function in women under the age of 40. At present，the pathogenesis of POI is still not very clear. More and more studies have found that the autophagy of granulosa cells induces the occurrence of POI. This paper will elaborate the research progress of the autophagy of granulosa cells of POI.