高度近视眼结构功能的改变及其与原发性青光眼发病的关系

Structural and functional changes in myopic eyes and their association with etiology of primary glaucoma

摘要:

青光眼是世界范围内第一大不可逆致盲性疾病，严重影响人们的视觉健康，但其发病的具体机制有待明确。大量研究表明，高度近视与青光眼特别是开角型青光眼的发病密切相关。高度近视眼的各个结构在眼轴延长中受到机械性伸展，可产生各种可能与青光眼发病相关的病理生理性改变，进而导致青光眼发病风险增加。本研究回顾分析近10年中英文文献，就高度近视眼各结构及功能的改变及其对青光眼发病的可能影响作一综述。

Abstract:

Glaucoma, as the first irreversible blinding disease worldwide, severely impairs people’s vision health, but with unclear pathogenic mechanism. A large quantity of researches have demonstrated the close relation between myopia and glaucoma, especially open-angle glaucoma. Structures of high myopic eyes are mechanically stretched in axial elongation and lead to various pathophysiologic changes associated with glaucomatous damages, so as to cause the increased onset risk for glaucoma. This study retrospectively analyzed papers published in the past 10 years at home and abroad and reviewed structural and functional changes in myopic eyes and their relationship with the etiology of primary glaucoma.