Abstract:Since 1988, string for original innovation and focusing on the national strategy of Healthy China, Zhibiao Wang and his team have steered to the core belief of "Diagnosis and treatments-Minimize harm to patients" and adhered to the integration of medicine and engineering, realizing American scholars’vision of in vivo treatment with extracorporeal focused ultrasound and making a series of significant breakthroughs of something out of nothing, including focused ultrasound-related basic research, technology research and development, equipment development, clinical application, standard/guideline/consensus formulation, talent training, and platform construction. Such breakthroughs have enabled China to keep leading the world in therapeutic ultrasound and form the prototype of the entire industry chain, exploring a development path that integrates higher education, research and development, manufacturing, and clinical applications of China’s original innovative medical equipment.