南昌市美沙酮维持治疗毒瘾患者抑郁情绪现状及影响因素分析

Prevalence of depression and the influential factors in drug users receiving methadone maintenance treatment in Nanchang province

摘要:

目的：探讨美沙酮维持治疗毒瘾患者的抑郁情绪现况及其影响因素，为进一步开展心理干预提供依据。方法：采用方便整群抽样的方法对2011年4月-2011年5月在南昌市东湖区美沙酮门诊美沙酮维持治疗毒瘾患者进行自编问卷及抑郁自评量表（Self-rating depression scale，SDS）测评。结果：南昌市美沙酮维持治疗毒瘾患者抑郁情绪的检出率为53.91%（207/384），SDS标准分平均为（55.03?11.052）分；多因素Logistic回归分析结果显示：女性（OR=0.243）、自认为经济状况好（OR=0.550）及AIDS相关知识了解多（OR=0.358）是美沙酮维持治疗毒瘾患者抑郁情绪发生的保护因素，而经济压力大（OR=1.585）及有毒瘾发作（OR=1.762）是导致其出现抑郁情绪的危险因素。结论：美沙酮维持治疗毒瘾患者抑郁情绪普遍存在，在临床治疗过程中，应根据患者的具体情况采取针对性的预防措施，从多个角度预防美沙酮门诊维持治疗患者抑郁情绪的发生。

Abstract:

Objective：To investigate the prevalence of depression and influential factors in drug users receiving methadone mainte－nance treatment in Nanchang，trying to find some evidence for more mental intervention. Methods：Drug users receiving metha-done maintenance treatment in Nanchang were selected by convenience cluster sampling and surveyed with questionnaire including self-rating depression scale（SDS） and self-made general questionnaire. Results：The overall prevalence of depression was 53.91%（207/384） in drug users receiving methadone maintenance treatment in Nanchang；the mean score of depression was （55.03?11.05）. Multivariate logistic analysis indicated that female（OR=0.243），good economic conditions in their own conceit （OR=0.550） and learning more about the knowledge of HIV/AIDS（OR=0.358） had a protective effect on depression；having a drug addiction attack（OR=1.762）and great economic pressure （OR=1.585） were risk factors for depression. Conclusion：The depression are common in drug users re－ceiving methadone maintenance treatment in Nanchang；therefore，we should take appropriate preventive measures in accordance with the patient’s specific situation in the clinical work，so as to prevent the occurrence of depression in drug users receiving methadone maintenance treatment.