恶性肿瘤危险因素的Logistic回归分析

Risk factors related to cancer by Logistic regressive analysis

摘要:

目的：了解恶性肿瘤的患病现况，探讨恶性肿瘤发病的危险因素，为制定恶性肿瘤的预防策略提供科学依据。方法：将确诊为恶性肿瘤患者的30人作为病例组，采用随机抽样的方法从4 290份正常人群的资料中抽取出430人作为对照组。采用统计软件SPSS17.0对460人的资料，先进行单因素分析，然后采用多因素非条件 Logistic回归模型筛选主要危险因素。结果：恶性肿瘤的患病率为0.69%，单因素分析显示年龄、年均收入、体重指数、文化程度、肿瘤家族史、水果蔬菜的饮食量、含油和脂肪多的食物频率、吸烟、饮酒及活动时间与肿瘤的发生有一定的关联，多因素显示年龄、体重指数、肿瘤家族史、水果蔬菜的饮食量、含油和脂肪多的食物、吸烟及活动时间是恶性肿瘤的危险因素。结论：肿瘤与生活方式有关，改变不良生活方式可以在一定程度上降低患肿瘤的风险。

Abstract:

Objective：To investigate the prevalence of cancer，assess the risk factors of cancer and offer the bases for making inter－ventional measures. Methods：30 cancer patients were taken as case group，and with the method of random sampling from the crowd of 4 290 normal data，430 people were extracted as control group. First，Chi-square and t-test were used to discuss the relationship be－tween the various factors，and then Logistic regression analysis was made by statistics software SPSS17.0 based on the results of the 460 people. Results:The prevalence of cancer was 0.69%. Sin－gle factor analysis results showed cancer was relate to age，av－erage annual income，BMI，educational level，family history of cancer，frequency of fruit and vegetable diet，oily and fatty food，smoking，drinking and activity time. Multivariate analysis showed that age，BMI，family history of cancer，frequency of fruit and vegetable diet，oily and fatty food，smoking and activity time were independent risk factors of cancer. Conclusion：Cancer is a kind of disease which correlates to life style；the essential measure to prevent cancer is to change unhealthy life style．