Objective:To evaluate the safety and effectiveness of treating residual stones after percutaneous nephrolithotomy (PCNL) with flexible fiberscope(choledochofiberscope) in outpatient department. Methods:The patients with residual stones after PCNL were treated by flexible fiberscopy to deal with residual stones. The removal of the residual stones and patients’tolerance were observed. Results:There were 22 cases in 52 cases(42.3%) whose residual stones were cleared completely in one time. The residual stones were cleared completely in 38 cases(73.1%). Conclusion:Application of flexible fiberscope(choledochofiberscope) in treating residual stones in outpatient department after PCNL is safe,economical and effective.