年龄对股骨近端几何结构的影响及意义

Effects of aging on the proximal femur geometry and their clinical significances

摘要:

目的：研究增龄因素对股骨近端几何结构的影响及意义。方法：将255例50岁以上妇女，依年龄分为A、B、C 3组，A组：156例，≤65岁；B组：55例，66～75岁；C组44例，＞75岁。依骨折情况分为非骨折组191例，骨折组64例。拍摄患者骨盆平片测量股骨近端几何结构参数。结果：（1）股骨颈轴长（Femoral neck axis length，FNAL）：A、B、C组间比较差异无统计学意义；（2）股骨颈中段宽度（Ｆemoral neck width，FNW）： A、C组比较差异有统计学意义；（3）股骨颈中段髓腔宽度（Ｆemoral medullary cavity width，FMCW）：A、B及A、C组比较差异有统计学意义；（4）股骨颈中段皮质厚度（Cortical thickness of femoral neck，FNCT）：A、B及A、C组比较差别有统计学意义；（5）FNCT比率及FNW与FNAL比率：A、B组及A、C组比较差异有统计学意义；（6）非骨折组与骨折组比较：年龄、FNAL、FNW、FMCW、FNCT、FNCT比率及FNW与FNAL比率２组间差别具有统计学意义；（7）颈干角（Ｎeck-shaft angle，NSA）各组间比较差异无统计学意义。结论：增龄因素导致股骨上端骨皮质变薄、髓腔扩大，骨折风险加大。

Abstract:

Objective：To study the effects of aging on the proximal femur geometry and their clinical significances. Methods：Totally 255 women over the age of 50 were divided into three groups by age：group A（n=156，aged under 65 years old），group B（n=55，aged between 66 and 75 years old），and group C（n=44，aged over 75 years old）. There were 191 women in non-fracture group and 64 women in fracture group. The patients’radiographs of the pelvis were used to measure the geometric parameters of the proximal femur. Results：（1）There was no significant statistical difference in the femoral neck axis length（FNAL） among group A，B and C. （2）There were significant statistical differences in the femoral neck width（FNW） between group A and C. （3）~（4）There were significant sta－tistical differences in femoral medullary cavity width（FMCW） and cortical thickness of femoral neck（FNCT） between group A，B and A，C. （5）There were statistical differences in the ratios of FNCT/FNW and FNW/FNL between group A，B and A，C. （6）There were significant statistical differences in age，FNAL，FNW，FMCW，FNCT，the ratios of FNCT/FNW and FNW/FNL between non-fracture group and fracture group. （7）There was no statistic difference in femoral neck-shaft angle（NSA） among group A，B and C and be－tween non-fracture group and fracture group. Conclusion：The risk of hip fracture is increased with aging due to thinning of cortiex and expansion of medullary cavity of the proximal femur.