Objective:To understand the mortality and death cause sequence of residents from diseases surveillance sites in Chongqing so as to provide scientific references for formulating strategies of disease control. Methods:Based on the data from 8 diseases survei-llance sites and international classification of diseases-10,death causes were classified. Crude mortality,age-standardized mortality and proportion of death causes were calculated. Chi-square test was used to compare rates. Results:Crude mortality of residents from diseases surveillance sites was 667.79/100 000 and age-standardized mortality was 473.39/100 000. Crude mortality of urban was higher than that of rural(?字2=224.89,P<0.001). Male’s crude mortality was higher than female’s(?字2=572.44,P<0.001). Crude mortality of aged more than 65 was higher than that of aged 0-14 and aged 15-64(?字2=114 118.60,P<0.001). The top five death causes were circular system disease(crude mortality was 249.01/100 000,proportion of death cause was 37.29%),tumor(164.36/100 000,24.61%),respiratory system disease(131.27/100 000,19.66%),injury and poisoning(53.78/100 000,8.05%) and digestive system disease(18.42/100 000,2.76%). Conclusions:Chronic non-communicable diseases are the diseases harming the residents in Chongqing. In order to actively control the harmfulness of chronic non-communicable diseases,all social parts should be mobilized to carry out health education,change the unhealthy life habits and strengthen environmental protection.