Objective:To understand the exposures of Benzenes in working environment of a shoe factory in Chongqing and to evaluate the risks to health. Methods:According to the established guidelines for harmful occupational chemical exposure risk assessment in Singapore,the exposure and health examination results of workers exposed to Benzenes were assessed. Results:Risk levels of Benzene,Toluene and Xylene were 3.24,2.57 and 2.40. Leukocyte abnormal rates were statistically different among workers with different types of work( χ2=7.236,P=0.027). Leukocyte abnormal rates were statistically different between male and female( χ2=9.334,P=0.002). There was no significant difference in erythrocytes,hemoglobin and platelet abnormal rate among workers(Fisher,P=0.455-0.777). Cancer risks of Benzene in sole workshop and heel workshop were significantly higher than the maximum level(10-4) stipulated by the U.S. environmental protection agency. Non-cancer risk of Toluene was higher in soles workshop than the other workshops and was 1.56 times higher than the standard. Conclusions:Serious cancer risks exist in sole and heel workshops,posing health threat to work-ers. The working environment should be improved to ensure the health of workers.