Objective:To analyze the disease constitution and death cause of hospitalized patients with cardiovascular diseases and to offer some epidemiology evidences for clinic and research of cardiology. Methods:Patients discharged from the cardiology department of the First Affiliated Hospital of Chongqing Medical University from January 2011 to December 2012 were retrospectively investigated and were divided into 4 groups:aged below 44,aged 45 to 59,aged 60 to 74 and aged over 75. Their disease constitution,death cause and proportion of heart failure and sudden cardiac death were analyzed. Results:There were 5 096 male and 5 212 female patients and the average age was (65.16±14.37) years. The top three diseases leading to hospitalization were coronary heart disease(CHD),hy-pertension and arrhythmia with constituent ratios of 41.29%,27.19% and 10.41% respectively. The top three diseases leading to hos-pitalization were similar between males and females,but different among different age groups:in 12-44 age group,the top three dis-eases were arrhythmia,hypertension and vital myocarditis;the top three diseases were the same between 45-49 age group and 60-74 age group;in 75-105 age group;the top three diseases were CHD,hypertension and sick sinus syndrome. There were 117 deceased among 10 308 inpatients and the mortality was 1.14%. The top three death cause diseases were CHD(71 cases,60.68%),hyperten-sion(17 cases,14.53%),rheumatic heart disease(15 cases,12.85%). The direct death causes diseases were heart failure(62 cases,52.99%) and sudden cardiac death(33 cases,28.21%). Conclusions:CHD and hypertension are the leading causes of hospitalization and death of patients with cardiovascular diseases,which should be better prevented and controlled.