13例胼胝体梗塞病例分析

Clinical analysis of corpus callosal infarction in 13 cases

摘要:

目的：探讨胼胝体梗塞的高危因素、病因、发病机制、临床表现以及影像学特点。方法：对13例胼胝体梗塞患者的临床资料进行回顾性分析。结果：胼胝体梗塞高危因素主要为高血压病、糖尿病、高脂血症；大动脉粥样硬化及其潜在机制参与胼胝体梗塞的形式。临床表现复杂多样，无特异性，缺乏典型胼胝体离断综合征表现。胼胝体梗塞部位以体部和压部为主，合并出现的其他部位脑梗塞也集中在后循环供血区。结论：胼胝体梗塞因其累及部位不同临床表现不同，高血压病、糖尿病、高脂血症为胼胝体梗塞不容忽视的重要高危因素，大动脉粥样硬化及其潜在机制参与本病的发生，头颅MRI对胼胝体梗塞及累及部位的定位诊断有指导作用。

Abstract:

Objective：To analyze the risk factor，etiology，pathogenesis，clinical manifestations and MRI feature of corpus callosal in－farction. Methods：Retrospective analysis was undertaken in 13 cases with corpus callosal infarction. Results：Risk factors of corpus callosal infarction included hypertension，diabetes mellitus，hyperlipidemia.Large arteries atherosclerosis and it’s potential mechanisms involved mainly in the corpus callosal infarction. Clinical manifestations were complex and diverse without specificity.Typical corpus callosum transection syndrome was not observed.Lesions were located mainly in the body and splenium of corpus callosum，always involving cerebral infarction of other parts in the posterior circulation blood supply area. Conclusions：Clinical manifestations of corpus callosalinfarction vary according to different lesion sites. Hypertension，diabetes mellitus，hyperlipidemia are the substantially important risk factors.Large arteries atherosclerosis and it’s potential mechanisms involve in the occurrence of the disease. MRI is helpful to locate clinically and treat corpus callosal infarction.