听力筛查未通过早产儿相关危险因素分析

Analysis of risk factors for premature infants with failed hearing screening

摘要:

目的：分析听力筛查未通过早产儿的危险因素。方法：收集665例早产儿听力筛查结果及临床资料，使用χ2检验行单因素分析、logistic回归行多因素分析，筛查出影响早产儿听力的危险因素。结果：20.8%未通过初筛。单因素分析表明：胎龄、出生体重、高胆红素血症、胆红素脑病、新生儿缺氧缺血性脑病（hypoxic-ischemic encephalopathy，HIE）、新生儿梅毒、化脓性脑膜炎、新生儿窒息可能与早产儿听力筛查未通过率有关（P＜0.05）。多因素分析显示：胎龄、出生体重、高胆红素血症、HIE、梅毒、窒息（OR分别为2.927、2.627、2.956、1.813、5.971、1.906）是早产儿听力筛查未通过的危险因素。结论：胎龄＜34周、出生体重＜1 500 g、高胆红素血症、HIE、梅毒、窒息是早产儿听力筛查未通过的危险因素，应尽早干预。

Abstract:

Objective：To explore the risk factors for premature infants with failed hearing screening. Methods：Clinical data of 665 premature infants were analyzed by Chi-square test and multivariate logistic regression analysis. Risk factors for premature infants who failed hearing screening were identified. Results：Totally 20.8% premature infants failed hearing screening. Single factor analysis indicated that gestational age，birth weight，hyperbilirubinemia，bilirubin encephalopathy，neonatal hypoxic-ischemic encephalopathy （HIE），neonatal syphilis，pyogenic meningitis，neonatal asphyxia might be the risk factors for failed hearing screening in premature infants（P＜0.05）. Multivariate analysis indicated that gestational age，birth weight，hyperbilirubinemia，HIE，syphilis，asphyxia were risk factors for failed hearing screening（respective OR：2.927，2.627，2.956，1.813，5.971，and 1.906）. Conclusion：Gestational age ＜34 weeks，birth weight<1 500 g，hyperbilirubinemia，HIE，syphilis，asphyxia are risk factors of failed hearing screening in premature infants and effective measures should be taken.