糖尿病视网膜病变手术后继发新生血管青光眼的危险因素

Risk factors of secondary neovascular glaucoma after vitrectomy for proliperative diabetic retinopathy

摘要:

目的：探讨增殖性糖尿病视网膜病变（proliferative diabetic retinopathy，PDR）经玻璃体切除手术后继发新生血管性青光眼（neovascular glaucoma，NVG）的相关危险因素。方法：入选288只因PDR而行玻璃体切除术的患眼，采用Fisher确切概率法比较各因素不同水平间NVG发生率的差异性。结果：（1）共有8只眼（2.8%）最终发展成为NVG；（2）Fisher确切概率法检验：PDRⅥ、术后玻璃体出血以及多次手术的P值分别为0.023、0.00２、0.006。结论：PDRⅥ、术后玻璃体出血以及多次手术是糖尿病视网膜病变（diabetic retinopathy，DR）手术后继发NVG的主要危险因素，病变早期进行手术以及对预防并发症的发生能降低继发NVG的发生率。

Abstract:

Objective：To observe the risk factors of secondary neovascular glaucoma（NVG） after vitrectomy for proliferative diabetic retinopathy（PDR）. Methods：A retrospective review was conducted on 288 eyes that underwent vitrectomy for PDR. Multiple factors were analyzed for their effect on secondary NVG using Fisher exact probability test. Results：Eight eyes（2.8%） developed secondary NVG. Fisher exact probability test showed that the P values of PDRⅥ，vitreous hemorrhage after vitrectomy and mutiple-surgery were 0.023，0.002，0.006 respectively. Conclusion：PDRⅥ，vitreous hemorrhage after vitrectomy and mutiple-surgery are main risk factors of secondary NVG after vitrectomy for PDR. Effective treatment at early stage of PDR and precaution of complications may reduce the incidence of secondary NVG.