Objective:To study the relationship between propagated sensations and surface electromyography along meridian caused by acupuncture at ‘Quchi’ acupoint. Methods:‘Quchi’ acupoint,non-acupoint of the meridian and non-acupoint control were acupunc-tured and propagated sensations were caused. Amplitude and muscle active duration of surface electromyography on brachioradialis were recorded. Results:There were significant differences in the positive frequency of propagated sensations along meridian at ‘Quchi’ acupoint,non-acupoint of the meridian and non-acupoint control(?字2=28.298,P=0.000). Positive frequency of propagated sensations along meridian was significantly higher at ‘Quchi’ acupoint and non-acupoint of the meridian than at non-acupoint control(?字2=24.783,P=0.000; ?字2=19.113,P=0.000). ‘Quchi’ acupoint,non-acupoint of the meridian and non-acupoint control were significantly different in the amplitude and muscle active duration(P=0.000). Amplitude and muscle active duration showed obvious variation at ‘Quchi’ acupoint than at non-acupoint of the meridian and non-acupoint control. Acupuncture at ‘Quchi’ acupoint,non-acupoint of the meridian and non-acupoint control all caused the amplitude variation of surface electromyography on brachioradialis(P=0.000). Conclusion:Synchronized surface electromyography on brachioradialis of propagated sensations along meridian caused by acupunc-ture at ‘Quchi’ acupoint is stronger than that caused by acupuncture at non-acupoint of the meridian and non-acupoint control and the effects of acupuncture at ‘Quchi’ acupoint on surface electromyography of brachioradialis show the acupoint specificity.