频发性房性早搏和房性心动过速的危险因素分析

Risk factors of frequent atrial premature beats and atrial tachycardia

摘要:

目的：探求频发性房性早搏（frequent atrial premature beats，FAPBs）和房性心动过速（atrial tachycardia，AT）的危险因素。方法：对2011年7月至2012年6月重庆医科大学附属第一医院动态心电图报告中以房性早搏（atrial premature beats，APBs）和AT为主的478例[FAPBs组230例， 偶发性房性早搏（sporadic atrial premature beats，SAPBs）组248例；AT组417例，APBs组61例]患者进行病例-对照研究分析，比较FAPBs和SAPBs组相关因素的构成比例差异，并将统计有差异的因素对FAPBs进行logistic回归分析，进而识别FAPBs相对SAPBs的危险因素；同理分析AT相对APBs的危险因素。结果：①年龄（OR=1.018，P=0.049）、高血压病程（OR=1.653，P=0.035）和心功能（OR=1.421，P=0.006）可能为FAPBs相对SAPBs的危险因素；②年龄（OR=1.06，P=0.000）和瓣膜病变（OR=1.584，P=0.012）可能是AT相对APBs的危险因素。结论：早期防治高血压、瓣膜病变可能减少FAPBs和AT的发生率，老年患者可不积极干预FAPBs和AT。

Abstract:

Objective：To explore risk factors of frequent atrial premature beats（FAPBs） and atrial tachycardia（AT）. Methods：Case-control study was conduced to check Holter reports of patients in the First Affiliated Hospital of Chongqing Medical University during July 2011 to June 2012. Totally 478 patients were enrolled including 230 patients with FAPBs and 248 patients with sporadic atrial premature beats（SAPBs） or putting another way，147 patients with AT and 61 patients with atrial premature beats（APBs）. Dif－ferences in constituent ratio among different factors between FAPBs and SAPBs were compared. The above statistically sig－nificant factors of FAPBs relative to SAPBs were analyzed by logistic regression and risk factors of AT relative to APBs were analyzed by the same way. Results：Age（OR=1.018，P=0.049），history of hypertension（OR=1.653，P=0.035） and heart function（OR=1.421，P=0.006） were potential risk factors of FAPBs relative to SAPBs. Age（OR=1.060，P=0.000） and valvular heart disease（OR=1.584，P=0.012） may be risk factors of AT relative to APBs. Conclusion：Early prevention and treatment of hypertension and valve lesions is likely to reduce the incidence of FAPBs and AT. Elderly FAPBs and AT patients needn’t be intervened actively.