羊膜移植联合丝裂霉素C治疗眼烧伤后睑球黏连的临床研究

Amniotic membrane transplantation combined with mitocmycin C in the treatment of symblepharon after severe eye burns

摘要:

目的：探讨羊膜移植联合丝裂霉素C治疗眼烧伤后睑球黏连的临床价值。方法：对27例27眼烧伤后睑球黏连的患者进行睑球黏连松解后，行羊膜移植联合丝裂霉素C重建球结膜和角膜表面。结果：27眼术后睑球黏连的病变均有好转，其中21眼术后恢复好，占77.8％，6眼虽然睑球黏连部分复发，但较术前明显改善，占22.2％，没有无效的病例。结论：对于眼烧伤后睑球黏连，羊膜移植联合丝裂霉素C重建眼表是一种理想的治疗方法，值得推广。

Abstract:

Objective：To discuss the clinical significance of amniotic membrane transplantation combined with mitomycin C in the treatment of symblepharon after severe eye burns. Methods：Twenty-seven patients（27 eyes） with severe symblepharon were treated with symblepharon resection then were transplanted with preserved human amniotic membrane combined with mitomycin C for bulbar conjunctiva and corneal surface reconstruction. Results：Symblepharon of 27 eyes was improved after operation，21 eyes（77.8%） ob－tained fine results；6 eyes（22.2%） had slight symblepharon recurrence，but were improved obviously compared with that of pre-opera－tion，no invalid case was found. Conclusion：Amniotic membrance transplantation combined with mitocmycin C is an ideal method in the treatment of symblepharon after severe eye burns and it is worthy to be popularized.