Objective:To evaluate the cortical bone densities of the palatal area using cone beam computed tomography(CBCT).Methods:CBCT scans of 107 adults(51 men,56 women,20 to 40 years old) were selected and reconstructed. Palatal cortical bone den-sity was measured in Hounsfield units(HU) at 28 sites. Repeated measures analysis of variance was used to test the intragroup differ-ences of cortical bone density,and the relationship between gender were analyzed by t-test. Results:The maximum value of palatal cortical bone densities was (976.24±138.66) HU,and the minimum value was (460.45±183.33) HU. There were significant differ-ences between the male and female groups in all sites(P<0.05),except Y0X0,Y8X0,Y8X6,Y12X6,Y20X6,Y20X9,Y24X6 and Y24X9. Palatal cortical bone densities showed a tendency to decrease posteriorly(P=0.000). The cortical bone densities at locations that 3 mm from the midpalatal suture to lateral side were greater than at midpalatal suture in the anterior palate(P<0.05). Conclusion:The distribution of palatal cortical bone densities in adults are obtained by CBCT. These data might provide valuable information for selecting sites to place mini-implants in the palate.