经导管封堵儿童先天性肺动静脉瘘的临床报告

A clinical report of transcatheter treatment for congenital pulmonary arteriovenous fistulas in children

摘要:

目的：总结儿童先天性肺动静脉瘘（pulmonary arteriovenous fistulas，PAVFs）的临床特点及介入治疗效果，进一步探讨经导管介入治疗PAVFs的方法及治疗原则。方法：回顾性分析重庆医科大学附属儿童医院2004年7月至2016年12月行心导管介入治疗的8例先天性PAVFs患儿，观察其临床表现、封堵效果及随访情况等。结果：8例患儿均封堵成功，术前术后经导管监测平均肺动脉压力无明显变化（P=0.757）；术后随访6月至10年，无残余瘘及其他并发症发生，将术前及术后末次随访血氧饱和度、血红蛋白量对比，差异有统计学意义（P<0.05）。结论：经导管介入封堵是治疗儿童PAVFs的有效且安全的方法。

Abstract:

Objective：To summarize the clinical features and intervention therapeutic effects on congenital pulmonary arteriovenous fistulas（PAVFs），and to explore the method and therapeutic principle of transcatheter closure of PAVFs. Methods：The clinic manifestation，efficiency of closure and follow-up of 8 PAVFs children in Children’s Hospital of Chongqing Medical University were retrospectively analyzed from July 2004 to December 2016. Results：Transcatheter closures of all cases were successful，and there was no significance in mean pulmonary arterial pressure before and after the treatment（P=0.757）. During the follow-up period of 6 months to 10 years，no residual shunts and other complications occurred，and compared to the pre-operation，the significance was existed in oxyhemoglobin saturation and hemoglobin during the last follow-up（P<0.05）. Conclusion：Transcatheter closure treatment is a safe and effective method for congenital PAVFs in children.