阴道子宫内膜间质肉瘤5年后局部复发病例临床病理观察（病例报道+文献复习）

Clinicalpathological observation of local recurrence cases after 5 years of vaginal endometrial sarcoma

摘要:

目的：研究阴道子宫内膜间质肉瘤局部复发的临床病理特征、免疫表型、诊断及鉴别诊断。方法：回顾分析1例原发于阴道的低级别子宫内膜间质肉瘤，随访5年后局部复发病例临床病理特征，并结合国内外文献复习。结果：本例原发于阴道的低级别子宫内膜间质肉瘤5年后局部复发的组织学形态和免疫组化与5年前的一致。国内外文献报道原发于阴道的子宫内膜间质肉瘤极少，迄今为止，中英文报道了14例，未见局部复发病例报道。结论：原发于阴道的子宫内膜间质肉瘤虽为低级别子宫内膜间质肉瘤，但肿瘤在切除术后数年仍可复发，建议对该病患者进行长期随访。

Abstract:

Objective：To study the clinicopathological characteristics，immunopheno-types，diagnosis and differential diagnosis of vagi－nal endometrial stromal sarcoma. Methods：A retrospective analysis of one case of low grade endometrial stromal sarcoma in the vagi－na was conducted and，was followed up 5 years later with the clinical pathological features of local recurrence cases combing with the review of literature at home and abroad. Results：The histological morphology and immunohistochemistry of local recurrence after 5 years of the low level endometrial sarcoma of the vagina were consistent with 5 years ago. There are few cases of endometrial sarcoma in the vagina，and 14 cases have been reported in both Chinese and English. So far，no local recurrence case has been reported. Conclusion：Although the primary vaginal endometrial stromal sarcoma is low grade endometrial stromal sarcoma（LGESS），the tumor may still relapse after a few years of resection，and it is suggested that patients with this disease should be followed up for a long time.