Objective:To investigate the positive incidence of post-traumatic stress disorder(PTSD) in Mosuo people. Methods:All the subjects were surveyed by the structural questionnaires:the MINI-international neuropsychiatric interview(MINI) using the stage random sampling method. Results:Totally 1 121 subjects completed the screening.The the positive incidence of PTSD was 3.57‰(95%CI=0.07‰ to 7.00‰),and the standardized rate was 3.62‰,with 5.29‰(95%CI=0‰ to 12.64‰) of men and 2.69‰(95%CI=0‰ to 6.43‰)of women.The positive incidence of 40 to 49 years old and over sixty in Mosuo people were 0.8% and 0.5%,respec-tively,higher than those of other age brackets(0.0%). Conclusion:PTSD is one of the factors that affects the social and economic development for Mosuo people. It is necessary to carry out research for its prevention.