MedGyn CO2冷冻治疗对宫颈病变的疗效及影响因素

Clinical effect of CO2 cryotherapy in treatment of cervical lesions and related influencing factors

摘要:

目的：观察CO2冷冻治疗对宫颈病变（包括慢性宫颈炎、宫颈上皮内瘤变）的疗效并分析相关影响因素。方法：收集2016年4月至2017年7月在重庆医科大学附属第二医院妇产科门诊接受宫颈CO2冷冻治疗且具有完整随访资料的患者129例，回顾性分析其疗效、并发症及其影响疗效的相关因素。结果：宫颈CO2冷冻治疗总有效率为80.6%（104/129），其中慢性宫颈炎有效率为86.1%（62/72），宫颈上皮内瘤变（cervical intraepithelial neoplasia，CIN）有效率为73.7%（42/57），宫颈病变合并人乳头瘤病毒（human papilomous viral，HPV）感染者冷冻治疗后HPV有效率达63.0%（51/81）。结论：CO2冷冻治疗对慢性宫颈炎、CIN与HPV感染的治疗是有显著效果的，值得在临床上推广应用。

Abstract:

Objective：To investigate the clinical effect of CO2 cryotherapy in the treatment of cervical lesions，including chronic cer－vicitis and cervical intraepithelial neoplasia（CIN），and related influencing factors. Methods：A total of 129 patients who underwent CO2 cryotherapy for cervical lesions in Department of Obstetrics and Gynecology in The Second Affiliated Hospital of Chongqing Medical University from April 2016 to July 2017 and had complete follow-up data were enrolled，and a retrospective analysis was performed for treatment outcome，complications，and influencing factors. Results：The overall response rate of cervical CO2 cryotherapy was 80.6%（104/129）；the patients with chronic cervicitis had a response rate of 86.1%（62/72），and those with CIN had a response rate of 73.7%（42/57）. The patients with cervical lesions and human papillomavirus（HPV） infection had an HPV remission rate of 63.0%（51/81）. Conclusion：CO2 cryotherapy has a marked clinical effect in the treatment of chronic cervicitis，CIN，and HPV infection and thus holds promise for clinical application.