中医三联疗法联合腹腔镜手术治疗输卵管性不孕的临床观察

Tri-combination therapy of traditional Chinese medicine combined with laparoscopy in the treatment of tubal infertility

摘要:

目的：观察中医三联疗法联合腹腔镜手术治疗输卵管性不孕的临床疗效。方法：将159例输卵管性不孕症患者随机分为对照组（n=79）和观察组（n=80）。对照组采用腹腔镜下盆腔粘连分离、输卵管疏通术；观察组在对照组的基础上，联合中医三联疗法（本科室协定方口服，中药保留灌肠，直流电药物离子导入）连续治疗3个月。随访6个月，记录2组患者术后中医证候积分、中医体征积分、输卵管通畅情况及术后妊娠情况，采用卡方检验评估其疗效差异。结果：观察组中医证候总有效率（97.50%）相比对照组（81.01%）有显著差异（P<0.05）；观察组中医体征总有效率（95.00%）相比对照组（78.50%）有显著差异（P<0.05）；观察组输卵管通畅率（83.75％）优于对照组（65.82%），2组差异有统计学意义（P<0.05）；观察组宫内妊娠率（62.50％）明显高于对照组（41.77％），2组差异有统计学意义（P<0.05）；观察组临床疗效总有效率（96.25%）优于对照组（83.54%），2组有显著差异（P<0.05）。结论：中医三联疗法联合腹腔镜手术治疗输卵管性不孕能改善中医证候、体征有效率，促进输卵管再通，提高宫内妊娠率，从而提高临床总有效率，具有重要的临床价值。

Abstract:

Objective：To investigate the curative effect of tri-combination therapy of traditional Chinese medicine cooperated with la－paroscopy on the treatment of tubal infertility. Methods：One hundred and fifty-nine patients who were diagnosed as tubal infertility in our hospital were randomly divided into control group（n=79） and observation group（n=80）. The patients in control group received pelvic adhesion separation and tubal dredge operation in the operative laparoscopy only，while patients in the observation group re－ceived this operation and after that，they were treated with tri-combination therapy of Chinese traditional medicine（oral medicine，enema，direct current（dc） drug iontophoresis） for 3 months continuously. After following-up for 6 months，the traditional Chinese medicine symptom score，the traditional Chinese medicine syndrome score，the degree of fallopian tube patency，and the rate of preg－nancy after treatment were all recorded. The Chi-Square test was used to evaluate the difference of curative effect between this two group. Results：Witha significant difference（P<0.05），traditional Chinese medicine symptom efficacy of observation group（97.50%）was superior to that of control group（81.01%），traditional Chinese medicine syndrome efficacy of observation group（95.00%） was superior to that of control group（78.50%），as well as the degree of fallopian tube patency between observation group（83.75%） and control group（65.82%）. Besides，there was also a significant difference（P<0.05） betweenobservation group（62.50％） and control group（41.77%） in the rate of pregnancy. Clinical efficacy rate of observation group（96.25%） was higher than that of control group（83.54%）（P<0.05）. Conclusion：Tri-combination therapy of Chinese traditional medicine cooperated with laparoscopy have a good clinical curative effect on the treatment of tubal infertility through improving the traditional Chinese medicine symptom score，the tra－ditional Chinese medicine syndrome score，the degree of fallopi－an tube patency，and the rate of pregnancy. It is worthy to be applied widely.