Objective:To discuss the clinical value of negative-pressure therapy in tension-free herniorrhaphy for the prevention of postoperative infection. Methods:A retrospective analysis was done on 1 553 cases of inguinal hernia admitted in our treatment from January 2011 to May 2016. The incisions infection rates before and after treatment were collected and compared. Results:In 1 553 cases,there were 55 cases of postoperative incision infection(3.54%),among which,30 cases were in the drainage group(1192 cases) with a incidence rate of 2.51% and 25 cases in the control group(361 cases) with a incidence rate of 6.93%. There was a correlation between the drainage and the incision infection,and the difference was statistically significant(P=0.00). Conclusion:It can effectively drain the exudates,promote the incision union and decrease postoperative infections by using negative-pressure drainage in the oper-ations of tension-free herniorrhaphy.