肥胖与摄盐量的关系研究

Correlationbetweenobesityandsaltintake

摘要:

目的：探讨肥胖与盐摄入量的关系。方法：2017年9月至2018年7月，招募年龄在18~55岁的非妊娠成都城市社区健康人群226名，其中男性92名，女性134名。收集健康人24h尿和血清，通过问卷调查收集一般信息。人群摄盐量通过检测24h尿钠排泄来估算。根据摄盐量将人群分为低盐摄入组（<12g/d）和高盐摄入组（≥12g/d）。根据体质指数和腹围定义超重和肥胖。受试者空腹状态下按由低到高的顺序分别品尝不同浓度的氯化钠溶液，并指出味觉能识别的最低氯化钠浓度，检测盐味觉阈值。结果：肥胖与高盐摄入密切相关，体质指数与摄盐量成正比（P<0.001，r=0.223）。超重和肥胖者盐味觉敏感性降低，摄盐量明显高于正常体质量者[（13.50±0.37）gvs.（15.34±0.47）g，P=0.002]，尤其是腹型肥胖患者。高盐摄入肥胖人群比例明显高于低盐摄入人群（78.64%vs.31.25%，P=0.016）。结论：肥胖与高盐摄入关系密切，超重和肥胖人群摄盐量增加，盐味觉敏感性降低。高盐摄入导致超重和肥胖患病率增加。

Abstract:

Objective：Toexploretherelationshipbetweensaltintakeandobesity.Methods：Twohundredandtwenty-sixhealthypeopleaged18-55yearsfromcommunitiesinChengduwereenrolledinthisstudyfromSeptember2017toJuly2018，including92malesand134non-pregnantfemales.24-hoururineandserumsampleswerecollectedfromhealthypeople，andgeneralinformationwasobtainedthroughquestionnairesurvey.Saltintakeinthepopulationwasestimatedbymeasuring24-hoururinesodiumexcretion.Accordingtothequantityofsaltintake，thepopulationwasdividedintolow-saltintakegroup（<12g/d）andhigh-saltintakegroup（≥12g/d）.Overweightandobesityweredefinedbybodymassindex（BMI）andabdominalcircumference.Thesubjectstasteddiffer－entconcentrationsofsodiumchloridesolutioninalow-to-highorderinthefastingstate，andpointedouttheminimumsodiumchlo－rideconcentration，thusdeterminingthesalttastethreshold.Results：Obesitywascloselyrelatedtohigh-saltintake，whileBMIwasinapositivecorrelationwithsaltintake（P<0.001，r=0.223）.Caseswithoverweightandobesityhadalowersalttastesensitivity，andtheirsaltintakewassignificantlyhigherthanthatofpeoplewithnormalbodyweight[（13.50±0.37）gvs.（15.34±0.47）g，P=0.002]，especiallyinabdominalobesitypatients.Theproportionofobesepeoplewassignificantlyhigherinthepopulationwithhighsaltin－takethaninthepopulationwithlowsaltintake（78.64%vs.31.25%，P=0.016）.Conclusion：Obesityiscloselyrelatedtohighsaltin－take.Overweightandobesepatientshaveincreasedsaltintakeandreducedsalttastesensitivity.Highsaltintakeleadstoanincreaseintheprevalenceofoverweightandobesity.