目的:根据区域内的糖尿病流行病学和糖尿病防治管理现状,利用信息化技术手段,通过患者血糖大数据分析,评价住院糖尿病患者血糖变化趋势,了解住院患者血糖监控的薄弱环节,从而指导临床血糖管理。方法:基于多中心的信息化血糖管理平台,于2016年9月至2018年1月收集重庆医科大学附属永川医院、重庆医科大学附属第二医院、重庆三峡中心医院共10608例住院糖尿病患者床旁血糖数据,采用群体模型(populationmodel)、个体模型(patientmodel)、人-时模型(patient-daymodel)分析住院糖尿病患者的血糖构成比:高血糖、低血糖、理想血糖占比等情况。结果:共收集快速床旁监测(point-of-caretesting,POCT)血糖数据253738个,采用群体模型分析,高血糖达38.3%,理想血糖仅占20.5%;采用个体模型分析,住院期间曾发生低血糖的患者占13.2%,其中曾出现严重低血糖的患者占1.2%,发生严重低血糖患者为低血糖患者的9.4%;采用人-时模型分析,理想血糖的患者人时数为49.6%,高血糖发生率为60.2%,严重高血糖发生率为18.8%。结论:住院糖尿病患者的理想血糖占比低,高血糖占比高,经过一段时间住院治疗后高血糖发生率呈下降趋势,但传统内分泌科被动会诊模式导致部分高血糖事件处理不及时。所有时间段均发生了低血糖事件,且部分患者发生了严重低血糖事件,午餐前与空腹为高发时段,晚餐前血糖监测频次低。
Objective:Toevaluatethebloodglucosechangesinhospitalizedpatientswithdiabetesbybigdataanalysisofpatientsus-inginformationtechnologyaccordingtotheepidemiologyofdiabetesandthecurrentstatusofprevention,treatment,andmanagementofdiabetesintheregion,tounderstandtheweaklinksofmonitoringhospitalizedpatients'bloodglucose,andtoguideclinicalbloodglucosemanagement.Methods:Basedonamulticenterinformationizedbloodglucosemanagementplatform,fromSeptember2016toJanuary2018,thebedsidebloodglucosedataof10608hospitalizedpatientswithdiabeteswerecollectedfromtheYongchuanHospi-talofChongqingMedicalUniversity,TheSecondAffiliatedHospitalofChongqingMedicalUniversity,andtheChongqingThreeGorgesCentralHospital.Thepopulationmodel,patientmodel,andpatient-daymodelwereusedtoanalyzethebloodglucoseconstituentratioofinpatientswithdiabetes:proportionsofpatientswithhyperglycemia,hypoglycemia,andidealbloodglucoselevel.Results:Atotalof253738point-of-caretestingbloodglucosemonitoringdatawerecollected.Thepopulationmodelanalysisshowedthattheprevalenceofhyperglycemiareached38.3%,andtheindividualswithanidealbloodglucoselevelonlyaccountedfor20.5%.Thepatientmodelanalysisshowedthat13.2%ofthepatientshadhypoglycemiaduringhospitalization;patientswithseverehypoglycemiaaccountedfor1.2%;patientswithseverehypogl-ycemiaaccountedfor9.4%ofpatientswithhypoglycemia.Thepatient-daymodelanalysisshowedthatthepatientswithanidealbloodglucoselevelaccountedfor49.6%;theincidenceofhyperglycemiawas60.2%;theincidenceofseverehyperglycemiawas18.8%.Conclusion:Theproportionofhospitalizeddiabetespatientswithanidealbloodglucoselevelislow,andthepro-portionofthosewithhyperglycemiaishigh.Afteraperiodofhospitalization,theincidenceofhyperglycemiaisdecreasing,butthetra-ditionalendocrinologypassiveconsultationmodecausesthatsomehyperglycemiaeventsarenotmanagedintime.Hypoglycemiaeventsoccurinalltimeperiods,andsomepatientshaveseverehypoglycemiaevents.Thehigh-riskperiodsofhypoglycemiaarebeforelunchandfasting.Thefrequencyofbloodglucosemonitoringbeforedinnerislow.
周蒙蒙,龚放,赵锡丽,杨刚毅,李志勇,杨增群,陈艳.重庆地区医院信息化血糖管理监测数据分析[J].重庆医科大学学报,2020,45(3):415-