新型冠状病毒肺炎24例临床分析

Clinical analysis of coronavirus disease 2019：a report of 24 cases

摘要:

目的：探讨新型冠状病毒肺炎（coronavirus disease 2019，COVID-19）的临床特点。方法：对确诊为COVID-19的24例病例临床资料进行回顾性分析。结果：在24例病例中，男性14例，女性10例，有武汉旅居史22例，占总数的91.7%；患者以发热、咳嗽为最主要临床表现，伴有头痛、乏力、全身酸痛等流感样症状。予支持对症、抗病毒、氧疗、糖皮质激素等综合治疗，全部患者痊愈或好转。病毒核酸转阴时间为（20.41±7.12） d。结论：结合流行病学史，发热，胸部CT肺炎表现及白细胞、淋巴细胞计数的正常或减少作为诊断本病的临床依据，T淋巴细胞计数的减少与患者的病情、预后有一定的相关性。治愈率高，但患者排毒时间长，须延长隔离时间。

Abstract:

Objective：To explore the clinical characteristics of coronavirus disease 2019（COVID-19）. Methods：The clinical data of 24 patients with COVID-19 were analyzed retrospectively. Results：Among the 24 patients，14 were male and 10 were female，and 22 had a history of living in Wuhan，accounting for 91.7%；fever and cough were the main clinical manifestations，accompanied by in－fluenza-like symptoms such as headache，fatigue，and muscle soreness. All patients were cured or improved by comprehensive treatment including supportive treatment，antiviral，oxygen therapy and glucocorticoid. The time of nucleic acid turning negative was （20.41±7.12） days. Conclusion：Combined with the epidemiological history，fever，CT pneumonia manifestation and the normal or decrease of leukocyte and lymphocyte count can be used as the clinical basis for diagnosing of the disease. The decrease of T lymphocyte count has a certain correlation with patients’ condition and prognosis. The cure rate is high，but the patient has a long duration of viral shedding，therefore，the isolation time must be prolonged.