湖北地区不同年龄、不同性别人群新型冠状病毒核酸检测结果回顾性分析

Retrospective analysis of 2019 novel coronavirus nucleic acid test results among individuals of different age and gender in Hubei Province

摘要:

目的：回顾性分析湖北地区新型冠状病毒（2019 novel coronavirus，2019-nCoV）核酸检测结果在不同年龄、不同性别间的差异，为新型冠状病毒肺炎（coronavirus disease 2019，COVID-19）疫情防控提供依据。方法：选定84 611名受检者为研究对象，分为0~、10~、20~、30~、40~、50~、60~、70~和80~共9个年龄段组，每个年龄段又分为男性组和女性组。将每组各个受检者的2019-nCoV核酸检测结果进行统计分析。结果：全部受检人群2019-nCoV核酸的阳性率为5.33%，以仅N基因阳性为主，占全部阳性病例的比重为66.42%。2019-nCoV核酸阳性率随着受检者年龄的增长而逐步增高，峰值出现在60~年龄段。女性2019-nCoV核酸整体阳性率（6.21%）明显高于男性（4.64%），差异有统计学意义（P＜0.05），主要是20~60岁年龄段的女性2019-nCoV核酸阳性率比男性高（各年龄段组内女性与男性比较，均P＜0.05）。结论：2019-nCoV核酸阳性率与年龄、性别相关，20~60岁女性比男性更易感染，70岁以前2019-nCoV核酸阳性率随受检者年龄的增长而逐步增高。

Abstract:

Objective：To retrospectively analyze the difference of 2019 novel coronavirus（2019-nCoV） nucleic acid test results among individuals of different age and gender in Hubei area，and provide prevention and treatment strategies of coronavirus disease 2019（COVID-19）. Methods：A total of 84 611 examinees were collected and divided into 9 groups by age：0-，10-，20-，30-，40-，50-，60-，70-，and 80-. Each age group was divided into male group and female group. The results of 2019-nCoV nucleic acid test in each group were statistically analyzed. Results：Positive rate of 2019-nCoV nucleic acid test was 5.33% in all examinees，among which only N gene positive results accounted for 66.42%. Positive rates of 2019-nCoV nucleic acid test were increased gradually with age，and reached the peak in 60- years old group. Positive rate of 2019-nCoV nucleic acid test in entire female group was 6.21% and signifi－cantly higher than that in entire male group（4.64%），and the differences were caused mainly by 20-60 years old female groups which had obviously higher positive rates of 2019-nCoV nucleic acid test than same age male groups（P＜0.05）. Conclusion：Positive rates of 2019-nCoV nucleic acid test are related to age and gender. The female aged 20-60 are more susceptible to infection than men. The positive rates of 2019-nCoV nucleic acid test were gradually increased with age before 70 years old.