Objective:To explore the nursing emergency strategy of district and county secondary hospitals in non-centralized coron-avirus disease 2019(COVID-19) treatment center in order to provide reasonable nursing emergency management reference for similar hospitals. Methods:During the diagnosis and treatment of COVID-19 in our hospital,nursing emergency strategies were timely imple-mented according to reasonable management of nursing human resource,enhancing nursing staff’s new knowledge and skills training,implementing scientific nursing quality control management,rational deployment of emergency protection materials,and providing personalized COVID-19 health education. Results:Prevention and control work of COVID-19 on nursing was carried out effectively and there was no record about misdiagnosis of infected patients,no infection of suspected patients and no infection of medical staff. Conclusion:Nursing managers should comprehensively combine responsibilities of non-centralized hospitals and limited nursing re-sources of district and county secondary hospitals,make all-round and multidimensional rational decisions,and adopt suitable nursing emergency strategies in accordance with regional conditions,so as to ensure the successful implementation of COVID-19 nursing pre-vention and control work.