急性肾损伤患者肾功能可复性评估指标的研究进展

Research progress of evaluation index on renal function renaturability in patients with acute kidney injury

摘要:

急性肾损伤（acute kidney injury，AKI）及急性肾脏病（acute kidney disease，AKD）是临床常见的危重症，目前改善全球肾脏病预后组织（Kidney Disease Improving Global Outcomes，KDIGO）指南仍将尿量与肌酐作为评估肾功能的标准。但尿量和肌酐有一定的延后性并受多种因素影响。AKI及AKD患者肾脏是否恢复可能是我们需要持续评估的内容。本文从肾脏功能常规指标、生物标志物、影像学方法3个方面对AKI及AKD患者肾功能可复性应用现状和进展进行综述。

Abstract:

Acute kidney injury（AKI） and acute kidney disease（AKD） are common clinical critical diseases. Currently，urine volume and creatinine are criteria for evaluating renal function in Kidney Disease Improving Global Outcomes（KDIGO） guidelines. However，urine volume and creatinine can be relatively delayed and can be influenced by many factors. Whether the kidney of AKI/AKD patients recover or not may be the content that needs continu－ous evaluation. This article reviewed the current situation and progress of renal function renaturability from aspects of routine indicators，biomarkers and imaging methods in AKI/AKD patients.