多重细胞因子在青光眼中的研究进展

Research progress of multiple cytokines in glaucoma

摘要:

房水由睫状体产生，是眼内重要的营养和循环物质，具有维持眼内压的功能。近年来，多位学者在青光眼、葡萄膜炎、年龄相关性黄斑变性等眼部疾病中检测到房水中细胞因子水平的变化。青光眼是世界范围内首位不可逆性致盲疾病，但其发病的具体机制尚不明确。有研究者提出，房水中的细胞因子变化可能在青光眼的发生发展过程中发挥重要作用。本文回顾性分析近期相关文献，就青光眼患者房水中几种常见的细胞因子改变特点及其在青光眼中的作用进行综述。

Abstract:

Aqueous humor is produced by the ciliary body. It is an important nutrient and circulating substance in the eye. It has the function of maintaining intraocular pressure. In recent years，many scholars have detected changes in cytokine levels in aqueous humor in eye diseases such as glaucoma，uveitis，and age-related macular degeneration. Glaucoma is the first irreversible blinding disease worldwide，but the specific mechanism of its occurrence is not clear. Some researchers have suggested that changes in cytokines in aqueous humor may play an important role in the occurrence and development of glaucoma. This article reviews and analyzes the re－cent relevant literature，and it reviews the changes of several common cytokines in the aqueous humor of glaucomatous patients and their role in glaucoma.