Objective:To summarize the main point and experience of Da Vinci robot laparoendoscopic single-site(R-LESS) on nurs-ing coordination in the comprehensive operative stage of endometrial cancer. Methods:Clinical data and nursing cooperation during operation of nine cases of Da Vinci R-LESS endometrial cancer surgery were retrospectively analyzed. Results:Operations of nine patients were successfully completed and the postoperative recovery was good. There were no medical and nursing complications dur-ing and after the operation. Conclusion:Professional robotic surgery team,thorough surgical plan,sufficient nursing preparation and skilled and smooth intraoperative nursing coordination ensure the successful implementation of R-LESS surgery.