脑库神经系统变性疾病的病理诊断

Neurodegenerative diseases pathological diagnosis in brain bank

摘要:

随着脑计划在国内的开展，脑库工作将在其中起重要作用。神经系统变性疾病为脑库相关疾病的重要组成部分，对其进行严格的神经病理诊断具有重要意义。本文结合作者在脑库工作中的经验，对常见神经系统变性疾病的病理特点进行重点概述，对近年来在阿尔茨海默病、原发性衰老相关性tau病等疾病的病理诊断进展进行介绍，力图建立脑库神经系统变性疾病病理诊断的标准化程序。

Abstract:

With the development of brain project in China, brain bank work will play an important role in the project. Neurodegenerative diseases contribute an important part in brain bank diseases, and it is of great significance to make a strict neuropathological diagnosis. In this article, combined with the author's working experience in brain bank, this paper focuses on summarizing the pathological characteristics of common neurodegenerative diseases, and introduces the pathological diagnosis progress of Alzheimer's disease, primary aging-related tauopathy and other diseases introduced in recent years, trying to establish a standardized procedure for pathological diagnosis of neurodegenerative diseases in brain bank.