儿童2型糖尿病规范化管理

Standardized management of type 2 diabetes mellitus in children

摘要:

随着肥胖儿童增多，儿童2型糖尿病（type 2 diabetes mellitus，T2DM）患病率明显增加。儿童T2DM不同于1型糖尿病（type 1 diabetes mellitus，T1DM）和成人T2DM。儿童T2DM具有独特的特点，β细胞功能下降更快，并发症发展更快。其并发症甚至比T1DM患儿更早出现，死亡率高于T1DM患儿。因此，加强儿童T2DM的规范管理和治疗，是儿童T2DM长期高质量生存的关键。

Abstract:

With the rapid increase of obesity in children and adolescents，the incidence of type 2 diabetes mellitus（T2DM） in children has increased rapidly around the world. T2DM in children is different not only from type 1 diabetes mellitus（T1DM） but also from T2DM in adults，and has unique features，such as a more rapidly progressive deterioration of islet beta-cell function and accelerated development of chronic diabetes complications. Chronic complications could occur earlier than those in children with T1DM，and the patient’s mortality is higher than that of T1DM children. Therefore，strengthening the standardized management and treatment of children with T2DM is the key to the long-term high-quality survival of children with T2DM.