醒后卒中的影像学研究进展

Advances in iconography of wake-up stroke

摘要:

我国最新居民致残和致死调查报告显示，卒中发病率高居首位，虽然近几年卒中致死率较前下降，但是因为疾病的致残性及后续康复带来的巨大社会支出，对卒中的探索及相关研究依然刻不容缓。急性缺血性卒中（acute ischemic stroke，AIS）占所有卒中的85%，醒后卒中（wake-up stroke，WUS）又占其中的20%左右。因在睡眠中发病，故具体发病时间不详。事实上，很多患者疾病发生在醒来前的很短时间，但治疗上却错失了溶栓或血管内治疗的机会，最终导致预后不良。目前针对WUS发病时间的研究越来越多，其中通过影像学手段推测WUS的发病时间指导其治疗尤为热门。本文对WUS的近期影像学研究进展作一综述。

Abstract:

According to the latest survey report on disability and death of residents in our country，the incidence of stroke ranks first. Although the probability of death from stroke has decreased in recent years，the disability of the disease and the huge social expenditures caused by subsequent rehabilitation make the exploration and related research of the stroke still urgent. Acute ischemic stroke（AIS) accounts for 85% of all strokes，and wake-up（WUS） strokes account for about 20% of them. Because of the onset during sleep，the specific time of onset is unknown. In fact，many patients have the onset within a short period of time before waking up，and they have missed opportunities for thrombolysis or endovascular treatment，which ultimately leads to a poor prognosis. At present，there are more and more researches on the onset time of WUS，among which，imaging methods to predict the onset time of stroke after waking up to guide the treatment of WUS are particularly popular. This article is a review of recent advances in iconography of WUS.