团块状灰度变化减轻子宫良性疾病聚焦超声消融术中的远场不良反应

Massive gray scale change benefits far-field adverse effects during focused ultrasound ablation in the treatment of benign uterine diseases

摘要:

目的 评估团块状灰度变化能否减轻子宫良性疾病聚焦超声消融术中的远场不良反应。方法 开展单中心回顾性临床观察研究，纳入重庆医科大学附属第二医院行聚焦超声消融术的40例子宫良性疾病。比较团块状灰度变化出现前后，在相同能量水平（最小不可耐受能量）下，术中即刻骶尾部或臀部疼痛、放射痛、会阴部痛、肛门胀痛的发生率及不良反应程度。结果 在相同能量水平（最小不可耐受能量）下，团块状灰度变化出现后术中即刻骶尾部或臀部疼痛、放射痛、会阴部痛、肛门胀痛的发生率及不良反应程度明显低于团块状灰度变化出现前（P<0.05）。结论 团块状灰度变化能减轻子宫良性疾病聚焦超声消融术中的远场不良反应。

Abstract:

Objective To explore whether the massive gray scale change（MGSC） can benefit far-field adverse effects during focused ultrasound ablation（FUA） in the treatment of benign uterine diseases.Methods In a single-center retrospective clinical observation study，40 patients with benign uterine diseases were treated with FUA in The Second Affiliated Hospital of Chongqing Medical University. Before and after the occurrence of MGSC，the incidence of far-field adverse effects such as sacrococcygeal or hip pain，radiation pain，perineal pain，anal distension pain and the levels of adverse effects were compared under the same energy level（the lowest intolerant energy）.Results Under the same energy level（the lowest intolerant energy），the incidence of sacrococcygeal or hip pain，radiation pain，perineal pain，anal distension pain and the levels of adverse effects immediately after the occurrence of MGSC were significantly lower than those before the occurrence（P<0.05）.Conclusion The MGSC can reduce far-field adverse effects during FUA in the treatment of benign uterine diseases.