剪切波弹性成像测量宫颈硬度的可重复性研究

Study on the repeatability of shear wave elastography in measuring cervical hardness

摘要:

目的 评价剪切波弹性成像（shear wave elastography，SWE）测量育龄期健康未育女性宫颈杨氏模量值的可重复性。方法 由同一名接受过SWE检测培训的高年资医师于同一天不同时间点，前后2次对100名处于育龄期但未育的健康女性宫颈行剪切波弹性成像，测量时选取宫颈4个位点：内口前唇（anterior lip of the inner mouth，IA）、内口后唇（posterior lip of the inner mouth，IP）、外口前唇（anterior lip of the outer mouth，EA）及外口后唇（posterior lip of the outer mouth，EP），获取育龄期健康未育女性宫颈杨氏模量值。使用组内相关系数（interclass correlation coefficient，ICC）评价检查者内可重复性，同时绘制Bland-Altman散点图评价测量一致性。结果 宫颈4个测量位点的前后2次测值均无统计学差异（P>0.05）；宫颈IA、EA、EP处杨氏模量值的组内相关系数分别为0.828、0.785、0.768，提示组内可重复性非常好；宫颈IP处杨氏模量值的组内相关系数为0.632，提示组内可重复性好；Bland-Altman散点图提示SWE测量宫颈4个位点杨氏模量值的组内一致性均为好。结论 SWE可用于宫颈硬度的测量，且在宫颈不同位点均具有良好的可重复性与一致性。

Abstract:

Objective To assess the repeatability of shear wave elastography（SWE） in the measurement of cervical Young's modulus in healthy childless women of childbearing age.Methods SWE was performed twice on the cervix of 100 healthy childless women of childbearing age on the same day and at different time points by the same senior physician who had received SWE testing training. The cervical Young's modulus value in healthy childless women of childbearing age was obtained by measuring the following four sites of cervix：anterior lip of the inner mouth（IA），posterior lip of the inner mouth（IP），anterior lip of the outer mouth（EA） and posterior lip of the outer mouth（EP）. Interclass correlation coefficient（ICC） was used to evaluate the intra-group repeatability，and Bland-Altman scatter plot was performed to assess the consistency of the measurement.Results There were no statistical significances between the two measurements of the four sites of cervix（P>0.05）. The intra -group correlation coefficients of Young's modulus at IA，EA and EP were 0.828，0.785 and 0.768 respectively，indicating quite satisfactory repeatability. The intra-group correlation coefficient of Young's modulus at IP was 0.632，indicating satisfactory repeatability. And Bland-Altman scatter plot indicated preferable intra-group consistency of Young's modulus measured by SWE at four sites of cervix.Conclusion SWE can be used to measure cervical hardness，and has good repeatability and consistency at different sites of cervix.