中医体质与心理症状的网络分析

Network analysis of traditional Chinese medicine constitutions and psychological symptoms

摘要:

目的 对中医体质与心理症状进行网络分析，构建二者的网络分析图，探究体质与心理症状的关系以及不同性别之间网络结构的差异，为临床心理疾病的早期预防和治疗提供依据。方法 以网络调查的方法收集调查对象的中医体质与心理症状，在R（Version 4.3.1）中使用qgraph进行分析和构建网络模型，利用graphical lasso对网络进行简化。使用bootnet对网络的稳定性进行检验，NetworkComparisonTest对不同性别之间的网络分析进行比较。结果 气虚质、阴虚质、痰湿质为该网络中具有高中心性的体质；人际关系敏感、焦虑、抑郁、强迫症状是具有高中心性的心理症状。该网络中强度中心性稳定性为0.75，接近中心性稳定性为0.67，中介中心性稳定性为0.28，均达到了可接受的程度。不同性别的中医体质与心理症状网络不存在显著差异。结论 不同性别的中医体质与心理症状网络是相似的，在该网络中气虚质、阴虚质和痰湿质是与心理症状相关的高中心性体质。在心理问题早期筛查中可结合患者的体质，针对体质进行调理，达到治未病的目的。

Abstract:

Objective To conduct a network analysis of traditional Chinese medicine（TCM） constitutions and psychological symptoms，construct a network analysis diagram of the two factors，explore the relationship between constitutions and psychological symptoms，as well as the differences in network structures between sexes，aiming to provide a basis for early prevention and treatment of clinical psychological disorders.Methods An online survey was used to collect the TCM constitutions and psychological symptoms of the participants. The data were analyzed and a network model was constructed using qgraph in R（Version 4.3.1）. The graphical lasso was used to simplify the network. The network stability was assessed using bootnet. NetworkComparisonTest was utilized to compare the network analyses between different sexes.Results Qi deficiency，Yin deficiency，and phlegm dampness were constitutions with high centrality in the network，while interpersonal sensitivity，anxiety，depression，and obsessive-compulsion were psychological symptoms with high centrality. The network demonstrated acceptable stability，with a strength centrality stability of 0.75，a closeness centrality stability of 0.67，and a betweenness centrality stability of 0.28. No significant differences were found in the network of TCM constitutions and psychological symptoms between different sexes.Conclusions The networks of TCM constitutions and psychological symptoms are similar across different sexes. Within this network，Qi deficiency，Yin deficiency，and phlegm dampness are constitutions with high centrality correlated with psychological symptoms. In the early screening for psychological problems，regulations targeting patients’ constitutions can achieve preventive treatment.