Objective:To study the effects of endotracheal tube occluder made from disposable infusion apparatus. Methods:Sixty-two patients underwent tracheotomy due to pulmonary contusion and respiratory insufficiency were enrolled and divided into two group according to different occluders. Thirty-seven patients in control group were treated with traditional occluders while 25 patients in ex-periment group were treated with occluders made from dispos-able infusion apparatus. The time for closing endotracheal tube,occluder drop incidence,secondary infection and the occurrence of airway foreign body were compared. Results:Experiment group showed a shorter time for closing endotracheal tube(Z=6.7,P=0.000) and a lower incidence of occluder drop compared with those of control group(P=0.017). There was no difference between the two groups in secondary infection and the occurrence of airway foreign body(P >0.05). Conclusion:The new endotracheal tube occluder made from disposable infusion apparatus overcomes defects of the traditional occluder. It has the potential to be widely used in clinic work.