Role and mechanism of microglia polarization on spinal cord injury

Abstract:

Spinal cord injury (SCI) is a common refractory disease and has been a focus of clinical research. It not only damages patients' physical and mental health, but also brings a heavy financial burden to their family and society. Although there are many researches on SCI, its exact mechanism still remains unclear. Therefore, effective treatments for SCI are in urgent needs. In recent years, relevant studies have shown that the inflammatory reaction caused by microglia polarization plays an important role in SCI. Therefore, this paper reviews the mechanism of microglia polarization in SCI, so as to provide new therapeutic strategies for SCI in the future.