Abstract:Gut microbiota interacts with the central neural system. Gut microbiota can regulate neural system, endocrine system, and immune system, etc., thus leading to the progress of neurodegenerative diseases. This paper reviews the research history of the gut microbiota, and focuses on its current progress in neurodegenerative diseases including Alzheimer's disease, Parkinson disease and amyotrophic lateral sclerosis. Accumulating evidence indicates that the gut microbial homeostasis may be destroyed in neurodegenerative diseases. Therefore, the maintenance of normal gut microbial homeostasis, such as by antibiotic and probiotic therapy and fecal transplantation, will provide new ways and ideas for the prevention and treatment of these kind of diseases.
