Abstract:Objective: To clarify the risk factors for venous thromboembolism (VTE) in women with ovarian malignant tumor. Methods: The data of 345 patients with ovarian malignant tumor admitted to the department of gynecological oncology of Sun Yat-sen Memorial Hospital, Sun Yat-sen University from January 1, 2015 to June 30, 2018 were analyzed retrospectively, among which 31 cases had VTE and 314 cases didn't. The patients'age, height, weight, surgical-pathological stage, pathological type and level of tumor markers were compared, so as to study the risk factors of VTE in patients with ovarian malignant tumor. Results: Our analysis showed that there were significant differences in surgical-pathological stage and age among the ovarian malignant tumor patients with VTE and those without (P<0.05), and there was no significant difference between body mass index (BMI) and pathology type (P>0.05). There was also no significant difference among tumor markers (AFP, CEA, CA125, CA199, CA724, HE4) (P>0.05).Logistic analysis suggested that surgical-pathological stage was an independent risk factor of VTE in women with ovarian malignant tumor. Conclusion: Age and surgical-pathological stage are risk factors of VTE in women with ovarian malignant tumor. The prevention and monitoring of thrombosis should be focused on the elderly and patients with advanced tumor.
