Abstract:Objective: To investigate the value of blood lactate dehydrogenase (LDH), aspartate aminotransferase (AST) and creatine kinase isoenzyme (CK-MB) in the diagnosis of severe adenovirus pneumonia (SAP) in children. Methods: A total of 159 children diagnosed with adenovirus pneumonia in the respiratory department of our hospital from January 1, 2018 to December 31, 2019, were divided into the ordinary adenovirus pneumonia group and the SAP group according to the severity of their condition. The levels of LDH, AST and CK-MB in blood were compared between the two groups, and the receiver operating curve (ROC curve) was used to compare the test efficiency of the three for SAP. Results: Compared with children with ordinary adenovirus pneumonia, the serum levels of LDH, AST and CK-MB in severe children were higher, and the differences were statistically significant (P<0.05). The ROC curve showed that LDH had the best diagnostic efficiency for SAP. Conclusion: Increased serum levels of LDH, AST and CK-MB are of great help to diagnose SAP, especially the changes in blood LDH.
