Study of gut microbiota dysbiosis induced depression and the underlying gut-brain mechanisms

Abstract:

Major depressive disorder (MDD) is a major mental disease which seriously affects human health. Increasing researches have shown that dysbiosis of gut microbiota plays an important role in the pathogenesis of MDD. We have carried out a series of researches to uncover the dysbiosis of gut microbiota in MDD and identify the key gut microflora that cause MDD, as well as the underlying molecular mechanisms. The present manuscript summarizes the research findings of our research group.