Abstract:Fetuin B, as a member of the cysteine protease inhibitors, was found to be a critical role in human metabolic disorders, inflammation, tumor and fertilization. The dysregulated of glucolipid metabolism is essentially associated with diabetes, non-alcoholic fatty liver disease and other metabolic disorders. Recent studies have shown that a relationship between fetuin B and glucolipid metabolism, the aim of this review is to summarize the development of the studies, better elucidate the physiological role of fetuin B, as well as provide the new conceptions on prevention, diagnosis, and therapy of metabolic disorders.
